|Healthcare Associated Infections|
|Methicillin-sensitive Staphylococcus Aureus (MSSA) Bacteraemias|
|For more information about this CEC program, click here|
Why is this important?
Healthcare associated infections (HAI) are a leading cause of preventable illness and death [1-5]. Staphylococcus aureus (S. aureus) bacteraemia (SAB) is a serious cause of morbidity and mortality worldwide. SAB is the most common cause of healthcare associated bacteraemias, with over half of all SAB episodes in Australia being attributed as a HAI . Typically, SABs that are able to be treated with common antibiotics, and demonstrate no resistance to the antibiotic, are referred to as being caused by methicillin-sensitive S. aureus (MSSA). National reporting of all healthcare-acquired SABs, including those caused by MSSA bacteraemias, was introduced in Australia in 2008. MSSA bacteraemia incidences and rates also are a key performance indicator for jurisdictions under the National Healthcare Agreement . This section will present MSSA SAB data for NSW, including both 'inpatient' and 'non-inpatient' HAI.
The HAI Program addresses the Australian Commission on Safety and Quality in Health Care's National Safety and Quality Health Service (NSQHS) Standards :
- 3.1 Developing and implementing governance systems for effective infection prevention and control to minimise the risks to patients of healthcare associated infections;
- 3.2 Undertaking surveillance of healthcare associated infections initiative;
- 3.3 Developing and implementing systems and processes for reporting, investigating and analysing healthcare associated infections, and aligning these systems to the organisation's risk management strategy;
- 3.4 Undertaking quality improvement activities to reduce healthcare associated infections through changes to practice.
 Klevens RM, Edwards JR, Richards CL, et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002. Public Health Rep. 2007; 122 (2):160-6.
 Jarvis WR, Jarvis AA, Chinn RY, et al. National prevalence of methicillin-resistant Staphylococcus aureus in inpatients at US health care facilities, 2010. Am J Infect Control. 2012; 40 (10):194-200.
 Sievert DM, Ricks P, Edwards JR, et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect Control Hosp Epidemiol. 2013; 34 (1):1-14.
 Huang SS, Septimus E, Kleinman K, et al. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013; 368 (24):2255-65.
 Graves N, Weinhold D, Tong E, et al. Effect on healthcare-acquired infection on length of hospital stay and cost. Infect Control Hosp Epidemiol. 2007; 28(3): 280-292.
 Collignon P, Nimmo GR, Gottlieb T, et al. Staphylococcus aureus bacteremia, Australia. Emerg Infect Dis. 2005; 11(4):554-561.
 Standing Council on Federal Financial Relations. National Healthcare Agreement 2012. Accessed November 2013 [Online]: http://www.federalfinancialrelations.gov.au/content/npa/healthcare/national-agreement.pdf
 Australian Commissionon Safety and Quality in Health Care (September 2011). National Safety and Quality Health Service Standards, ACSQHC, Sydney www.safetyandquality.gov.au/publications/national-safety-and-quality-health-servicestandards/
Between Jan 2011 and Jun 2016, the annual rate of MSSA bacteraemia in NSW hospitals decreased from 0.79 per 10,000 occupied bed days (OBDs) in 2011 to 0.50 in 2015 (Chart MS01). Despite fluctuating monthly infection rates, a steady declining trend in State’s annual rates is observed.
Patients who develop bacteraemias, such as MSSA, are more likely to suffer complications that result in a longer hospital stay and an increased cost of hospitalisation. Serious infections may also result in death. The aim, therefore, is to minimise the total number of bacteraemias.
What we don't know
S. aureus is a normal human commensal that can also behave as a versatile and virulent pathogen . Underlying patient factors are important in determining the likelihood of pathogen transmission and complicated bloodstream infection. Improved understanding of these patient factors requires additional data collection and analysis. The analysis of MSSA infection data by; its origin whether it is hospital- or community-acquired, hospital peer group classification, or a change in severity stages during hospital admission may shed some light on the MSSA transmission process.In addition, the trend analysis comparing rates for MRSA and MSSA bacteraemias may identify differences in the pattern of SAB infections over time.
|Chart MS01 - Methicillin-sensitive Staphylococcus aureus (MSSA) Bacteraemias|
Drafted by: CEC eChartbook team and CEC Clinical Governance Directorate
Data analysis by: CEC eChartbook team
Reviewed by: CEC Clinical Governance Directorate
Edited by: CEC eChartbook team
Clinical Excellence Commission [access year]. eChartbook Portal: Safety and Quality of Healthcare in New South Wales. Sydney: Clinical Excellence Commission. Available at: http://www.cec.health.nsw.gov.au/echartbook/cec-indicators-intro-chartbook/hai-mssa Accessed (insert date of access).
© Clinical Excellence Commission 2016
This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part may be reproduced without prior written permission from the Clinical Excellence Commission (CEC). Requests and enquiries concerning reproduction and rights should be directed to the Director, Corporate Services, Locked Bag 8, Haymarket NSW 1240.
Evidence-base for this initiative
Healthcare Associated Infection, NSW MOH - www.health.nsw.gov.au/professionals/hai/
|Admin Status:||Current, Jun 2016|
|Indicator Name:||Methicillin-sensitive S. aureus (MSSA) bacteraemias|
|Description:||Methicillin-sensitive S. aureus (MSSA) bacteraemia rate per 10,000 occupied bed days (public hospitals only), NSW, Jan 2011-Mar 2016|
|Clinical Area:||Initiatives in safety and quality health care|
|Data Inclusions:||All methicillin-sensitive S. aureus (MSSA) bacteraemias (including inpatient & non-inpatient)|
|Numerator:||Total number of methicillin-sensitive S. aureus (MSSA) bacteraemias (including inpatient & non-inpatient)|
|Denominator:||Total number of bed days|
|Standardisation:||None (crude bacteraemia rate per 10,000 occupied bed days calculated)|
|Data Source:||Clinical Excellence Commission and NSW Ministry of Health|